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Brief Detail About AVP Gene

One of the millions of genes present inside our body, and richly associated with our health and water weight, is the AVP Gene. This gene has the task of providing instructions for making a hormone, named as vasopressin, as well as antidiuretic hormone. So, it wouldn’t be wrong if we call AVP Gene as a hormone gene. The Antidiuretic Hormone (ADH) starts out as a larger molecule called a preprohormone, and further produces an active hormone along with several related proteins. These proteins richly affect your health and water weight. Remember, the location of this preprohormone is the hypothalamus, which is one of the foremost regions of the brain. 

The central role of AVP Gene is to balance the body’s water with the help of determining the water excretion in urine form. If the fluid intake of a person is low or high than average, the gene actives and plays its role. 

Health Conditions Related to Genetic Changes

Every gene present in your body positively influences your health. But when the gene mutation process takes place, it results in numerous health conditions. Similarly, when the AVP Gene’s mutation happens, it results in Neurohypophyseal Diabetes insipidus. 

For this health condition, at least 60 mutations of the AVP Gene have been diagnosed. And almost all of these mutations change single protein building blocks. The main characteristic of Neurohypophyseal Diabetes Insipidus is problems with water balancing. 

Location

The Cytogenetic Location of AVP Gene is 20p13. In other words, it is located in Chromosome 20 at position 13. While the molecular location is base pairs 3,082,556 to 3,093,521. 

Common Names For AVP Gene

AVP refers to Arginine Vasopressin. But this name is not enough to refer to its specifications. Therefore, there are some other common names for this gene, that includes:

• ADH
• Antidiuretic Hormone
• ARVP 
• AVP-NPII
• AVRP
• NEU2_HUMAN
• Neurohypophyseal
• Vasopressin-neurophysin 2-copeptin
• Vasopressin-neurophysin 2-copeptin preprotein
• Vasopressin-neurophysin II-copeptin
• VP

In the end, let’s check out the tests of AVP. The main objective of this test is to examine the utility of AVP gene analysis in confirming the diagnosis of FNDI. A PCR, abbreviated as Polymerase Chain Reaction, is required for AVP Gene amplification and sequencing.