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Genetic Affect on Aging

The term aging refers to becoming older with clear skin and internal changes in the human body. Everyone who is alive will get older one day. But, what time it will be? No answer, right? Here we will discuss the aging process of human beings. Read the blog till the end and hopefully, you will be very much acknowledged.

The most prominent thing that affects your aging is the genes inherited from your parents. Since the genes are made up of DNA, so their mutation in your body is pretty much effective. That is why your DNA predicts more about you than the way you look. Scientists have given a genetic theory of Aging which says that “your genes and the mutation among those genes are responsible for how long you’ll live. There are a few other error theories that include:

• Wear and Tear Theory of Aging
• Rate of Living Theory of Aging
• Protein Cross-Linking Theory of Aging
• Free Radical Theory of Aging
• Somatic Mutation Theory of Aging
• Immunological Theory of Aging
• Endocrine Theory of Aging

Since our main theory that will be discussed here is the genetic theory of Aging, so let us briefly study the key concepts of it.

Telomeres

The DNA present at the end of each chromosome refers to telomeres. This DNA isn’t a protein decoder itself but performs a protective function. Telomeres prevent the DNA ends from attaching or forming a circle. One thing to be remembered about telomeres is that it is effective in every type of cell except the white blood cells. In total, three types of sequences of telomere are discovered. In humans, the telomeres sequence is TTAGG.

Longevity Genes

These types of genes are associated with living longer. That’s why they are called longevity genes. Longevity Genes have two common types that are directly linked with each other. These two gene types are SIRT1 and SIRT2. SIRT1 and SIRT2, these both are the genes that are related to aging. Because of these genes, your aging is linked to genetics. 

Cell Senescence

The decaying of human cells over time is known as cell senescence. Cell Senescence is related to telomeres and can shorten them. Cell senescence often causes apoptosis, which is the second name of cell suicide. In apoptosis, the damaged and old cells are removed.

Epigenetics

This factor is something interesting to discuss. Epigenetics is the expression of genes on the basis of which, a gene may be present but can either be turned on or off. Epigenetics works on only a few genes. Because only few genes are present in our body that can be turned on or off for a certain period of time. 

Another key factor that is linked to the genetic theory is Stem Cells.